GCM2
Reaktivität: Human
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 750
Applikationshinweise
Suggested dilutions: Western blotting: 1.500-1.3000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
Biohazard Informations: This product contains thimerosal which is hazardous.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
GCM2
(Glial Cells Missing Homolog 2 (GCM2))
Andere Bezeichnung
glial cells missing homolog 2
Hintergrund
This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination.The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity.The protein is a transcription factor that acts as a master regulator of parathyroid development.It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells.Mutations in this gene are associated with hypoparathyroidism.[provided by RefSeq]