F9
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.250
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
Biohazard Informations: This product contains thimerosal which is hazardous.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
Coagulation Factor IX (F9)
Andere Bezeichnung
Factor IX
Hintergrund
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen.This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds.The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII.Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.[provided by RefSeq]