NQO1 Antikörper (AA 213-274)

Produktnummer ABIN1886199

Dieses Anti-NQO1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NQO1 in WB, IHC und IF. Geeignet für Human.

Kurzübersicht für NQO1 Antikörper (AA 213-274) (ABIN1886199)

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NQO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-NQO1 Antikörper

Bindungsspezifität: AA 213-274

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 213 and 274 of NQO1

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu NQO1

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Andere Bezeichnung: NQO1

Hintergrund: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase.This FAD-binding protein forms homodimers and reduces quinones to hydroquinones.This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species.Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer.Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[provided by RefSeq]

Molekulargewicht: 31 kDa

Gen-ID: 1728

NCBI Accession: NM_000903, NP_000894