Factor VII Antikörper (AA 209-444)

Produktnummer ABIN1886186

Der Kaninchen Polyklonal Anti-Factor VII-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Factor VII in Proben von Human und Maus zu detektieren.

Kurzübersicht für Factor VII Antikörper (AA 209-444) (ABIN1886186)

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Factor VII Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Factor VII Antikörper

Bindungsspezifität: AA 209-444

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 209 and 444 of Factor VII

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Factor VII

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Andere Bezeichnung: Factor VII

Hintergrund: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis.This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis.Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond.In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa.Alternative splicing of this gene results in 2 transcripts.Defects in this gene can cause coagulopathy.[provided by RefSeq]

Molekulargewicht: 52 kDa

Gen-ID: 2155

NCBI Accession: NP_000122, NM_000131

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling