CLDN14 Antikörper (AA 177-189)

Produktnummer ABIN1886114

Der Kaninchen Polyklonal anti-CLDN14 Antikörper wird verwendet zum Nachweis von CLDN14 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für CLDN14 Antikörper (AA 177-189) (ABIN1886114)

Target: CLDN14 (Claudin 14 (CLDN14))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLDN14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CLDN14 Antikörper

Bindungsspezifität: AA 177-189

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 177 and 189 (O95500) of Claudin 14

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 1 x PBS, 40 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu CLDN14

Target: CLDN14 (Claudin 14 (CLDN14))

Andere Bezeichnung: claudin 14

Hintergrund: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet.The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands.The encoded protein also binds specifically to the WW domain of Yes-associated protein.Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness.Several transcript variants encoding the same protein have been found for this gene.[provided by RefSeq]

Molekulargewicht: 26 kDa

Gen-ID: 23562

NCBI Accession: NM_012130, NP_036262

Pathways: Cell-Cell Junction Organization, Hepatitis C