STIP1 Antikörper (AA 1-270)
Kurzübersicht für STIP1 Antikörper (AA 1-270) (ABIN1885874)
Target
Alle STIP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-270
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Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 270 of STIP1
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Applikationshinweise
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))
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Andere Bezeichnung
- STIP1
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Hintergrund
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STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A, MIM 140550) and HSP90 (see HSP90AA1, MIM 140571) in protein folding.It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70.STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM]
Synonyms: HOP, IEF-SSP-3521, P60, STI1, STI1L -
Molekulargewicht
- 63 kDa
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Gen-ID
- 10963
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NCBI Accession
- NM_006819, NP_006810
Target
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