m1ip1
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
Suggested dilutions: Western blotting: 1.500-1.3000 Immunofluorescence: 1.100-1.200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
Biohazard Informations: This product contains thimerosal which is hazardous.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
m1ip1
(Mid1-Interacting Protein 1 (m1ip1))
Andere Bezeichnung
Slap
Hintergrund
Adapter protein, which negatively regulates T-cell receptor (TCR) signaling.Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells.Involved in the negative regulation of positive selection and mitosis of T-cells.May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.