Prosaposin Antikörper (AA 1-220)

Produktnummer ABIN1885798

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Prosaposin in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Prosaposin Antikörper (AA 1-220) (ABIN1885798)

Target: Prosaposin (PSAP)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prosaposin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Prosaposin Antikörper

Bindungsspezifität: AA 1-220

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 220 of PSAP

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Prosaposin

Target: Prosaposin (PSAP)

Andere Bezeichnung: PSAP

Hintergrund: This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D.Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites.Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups.The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy.Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq]

Molekulargewicht: 58 kDa

Gen-ID: 5660

NCBI Accession: NP_002769, NM_002778

Pathways: Positive Regulation of Endopeptidase Activity