RANBP1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Suggested dilutions: Western blotting: 1.500-1.3000 Immunofluorescence: 1.100-1.200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
Biohazard Informations: This product contains thimerosal which is hazardous.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
RANBP1
(RAN Binding Protein 1 (RANBP1))
Hintergrund
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN.RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP.RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1).The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog.In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.[provided by RefSeq]