DC-SIGN/CD209 Antikörper (Extracellular Domain)

Produktnummer ABIN1885521

Der Maus Monoklonal anti-DC-SIGN/CD209 Antikörper (ABIN1885521) detektiert spezifisch DC-SIGN/CD209 in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DC-SIGN/CD209 Antikörper (Extracellular Domain) (ABIN1885521)

Target: DC-SIGN/CD209 (CD209) (CD209)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-DC-SIGN/CD209 Antikörper

Bindungsspezifität: Extracellular Domain

Aufreinigung: Immunoaffinity chromotography purified IgG

Immunogen: Raised against a recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN (1).

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: -20 °C

Informationen zur Lagerung: Can be stored at -20 °C, stable for one year.

Haltbarkeit: 12 months

Details zu DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Andere Bezeichnung: DC-SIGN

Hintergrund: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes , where DCs hand over HIV to CD4+ T lymphocytes.DCs also amplify the amount of virus and extend the duration of viral infectivity.Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN.ICAM-3 is the natural ligand for DC-SIGN.A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently.DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR (8).The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.
Synonyms: DC-SIGN (5D7), Dendritic cell-specific ICAM-3-grabbing nonintegrin 1

UniProt: Q9NNX6