USP22 Antikörper

Produktnummer ABIN1882289

Es sind 3+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-USP22 Antikörper wird verwendet zum Nachweis von USP22 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für USP22 Antikörper (ABIN1882289)

Target: USP22 (Ubiquitin Specific Peptidase 22 (USP22))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser USP22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1154CT13-1-3-1

Produktdetails anti-USP22 Antikörper

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged USP22 protein was used to produced this monoclonal antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-USP22 Antikörper (ABIN1882289)

Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." in: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).

Zhang, Varthi, Sykes, Phillips, Warzecha, Zhu, Wyce, Thorne, Berger, McMahon: "The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression." in: Molecular cell, Vol. 29, Issue 1, pp. 102-11, (2008) (PubMed).

Lee, Kim, Shin, Park, Chung, Baek: "The expression patterns of deubiquitinating enzymes, USP22 and Usp22." in: Gene expression patterns : GEP, Vol. 6, Issue 3, pp. 277-84, (2006) (PubMed).

Details zu USP22

Target: USP22 (Ubiquitin Specific Peptidase 22 (USP22))

Andere Bezeichnung: USP22

Hintergrund: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

Molekulargewicht: 59961

NCBI Accession: NP_056091

UniProt: Q9UPT9