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PAPSS1 Antikörper (N-Term)

This anti-PAPSS1 antibody (ABIN1882107) is a Rabbit Polyclonal antibody detecting PAPSS1 in WB. Suitable for Human.
Produktnummer ABIN1882107

Kurzübersicht für PAPSS1 Antikörper (N-Term) (ABIN1882107)

Target

Alle PAPSS1 Antikörper anzeigen
PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Reaktivität

  • 25
  • 3
  • 2
Human

Wirt

  • 22
  • 3
Kaninchen

Klonalität

  • 23
  • 2
Polyklonal

Konjugat

  • 13
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PAPSS1 Antikörper ist unkonjugiert

Applikation

  • 16
  • 12
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Klon

RB5122
  • Bindungsspezifität

    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1-30, N-Term

    Homologie

    M

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This PAPSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PAPSS1.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Haltbarkeit

    6 months
  • Gillies, Lee, Long, Ktistakis, Pyne, Pyne: "The sphingosine 1-phosphate receptor 5 and sphingosine kinases 1 and 2 are localised in centrosomes: possible role in regulating cell division." in: Cellular signalling, Vol. 21, Issue 5, pp. 675-84, (2009) (PubMed).

    Venkatachalam: "Human 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase: biochemistry, molecular biology and genetic deficiency." in: IUBMB life, Vol. 55, Issue 1, pp. 1-11, (2003) (PubMed).

    Xu, Otterness, Freimuth, Carlini, Wood, Mitchell, Moon, Kim, Xu, Siciliano, Weinshilboum: "Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1) and PAPSS2: gene cloning, characterization and chromosomal localization." in: Biochemical and biophysical research communications, Vol. 268, Issue 2, pp. 437-44, (2000) (PubMed).

    Venkatachalam, Akita, Strott: "Molecular cloning, expression, and characterization of human bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase and its functional domains." in: The Journal of biological chemistry, Vol. 273, Issue 30, pp. 19311-20, (1998) (PubMed).

    Faiyaz ul Haque, King, Krakow, Cantor, Rusiniak, Swank, Superti-Furga, Haque, Abbas, Ahmad, Ahmad, Cohn: "Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse." in: Nature genetics, Vol. 20, Issue 2, pp. 157-62, (1998) (PubMed).

    Girard, Baekkevold, Amalric: "Sulfation in high endothelial venules: cloning and expression of the human PAPS synthetase." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 12, Issue 7, pp. 603-12, (1998) (PubMed).

  • Target

    PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

    Andere Bezeichnung

    PAPSS1

    Hintergrund

    Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes. SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2.

    Molekulargewicht

    70833

    NCBI Accession

    NP_005434

    UniProt

    O43252

    Pathways

    Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process
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