ICAM1 Antikörper (C-Term)

Produktnummer ABIN1882096

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ICAM1 in WB und FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für ICAM1 Antikörper (C-Term) (ABIN1882096)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ICAM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: RB20472

Produktdetails anti-ICAM1 Antikörper

Bindungsspezifität: AA 488-514, C-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ICAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 488-514 amino acids from the C-terminal region of human ICAM1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ICAM1 Antikörper (ABIN1882096)

Fang, Yang, Yuan, Gao, Zhou, Chen, Xu: "Myocardin-related transcription factor A mediates OxLDL-induced endothelial injury." in: Circulation research, Vol. 108, Issue 7, pp. 797-807, (2011) (PubMed).

Denkers, de Jong-de Boer, Beelen, Ossenkoppele, Langenhuijsen: "VLA molecule expression may be involved in the release of acute myeloid leukaemic cells from the bone marrow." in: Leukemia research, Vol. 16, Issue 5, pp. 469-74, (1992) (PubMed).

Rössler, Neuchrist, Kitz, Scheiner, Kraft, Lassmann: "Expression of leucocyte adhesion molecules at the human blood-brain barrier (BBB)." in: Journal of neuroscience research, Vol. 31, Issue 2, pp. 365-74, (1992) (PubMed).

Details zu ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Andere Bezeichnung: ICAM1

Hintergrund: ICAM1 is a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.

Molekulargewicht: 57825

NCBI Accession: NP_000192

UniProt: P05362

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling