UBE2K Antikörper (AA 109-139)

Produktnummer ABIN1882088

Der Kaninchen Polyklonal Anti-UBE2K-Antikörper wurde für WB, IF und IHC (p) validiert. Er ist geeignet, UBE2K in Proben von Human und Maus zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für UBE2K Antikörper (AA 109-139) (ABIN1882088)

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB4144

Produktdetails anti-UBE2K Antikörper

Bindungsspezifität: AA 109-139

Homologie: B

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This HIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-139 amino acids from the Central region of human HIP2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. IHC-P: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-UBE2K Antikörper (ABIN1882088)

Furukawa, Kubo, Kikuchi, Tokura, Fujita, Sakurabayashi: "Regulation of macrophage-specific gene expression by degenerated lipoproteins." in: Electrophoresis, Vol. 21, Issue 2, pp. 338-46, (2000) (PubMed).

Kikuchi, Furukawa, Kubo, Tokura, Hayashi, Nakamura, Matsuda, Sakurabayashi: "Induction of ubiquitin-conjugating enzyme by aggregated low density lipoprotein in human macrophages and its implications for atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 20, Issue 1, pp. 128-34, (2000) (PubMed).

Petersén, Mani, Brundin: "Recent advances on the pathogenesis of Huntington's disease." in: Experimental neurology, Vol. 157, Issue 1, pp. 1-18, (1999) (PubMed).

Details zu UBE2K

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Andere Bezeichnung: HIP2

Hintergrund: HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.

Molekulargewicht: 22407

NCBI Accession: NP_001104582, NP_001104583, NP_005330

UniProt: P61086