DUSP13-L184 (AA 169-198), (C-Term) Antikörper

Produktnummer ABIN1882074

Zitiert in 3+ Publikationen. Der Kaninchen Polyklonal anti-DUSP13-L184 Antikörper (Klon RB5910) (ABIN1882074) detektiert spezifisch DUSP13-L184 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DUSP13-L184 (AA 169-198), (C-Term) Antikörper (ABIN1882074)

Target: DUSP13-L184

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB5910

Produktdetails

Bindungsspezifität: AA 169-198, C-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This DUSP13-L184 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the C-terminal region of human DUSP13-L184.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen

Zhao, Fiske, Kawakami, Li, Fisher: "Regulation of MITF stability by the USP13 deubiquitinase." in: Nature communications, Vol. 2, pp. 414, (2011) (PubMed).

Deloukas, Earthrowl, Grafham, Rubenfield, French, Steward, Sims, Jones, Searle, Scott, Howe, Hunt, Andrews, Gilbert, Swarbreck, Ashurst, Taylor, Battles, Bird, Ainscough, Almeida, Ashwell, Ambrose et al.: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, (2004) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Antigendetails

Target: DUSP13-L184

Hintergrund: Dual-specificity phosphatases, a subfamily of protein-tyrosine phosphatases, play important roles in signal transduction, cell cycle progression, and tumor suppression. The cDNA encoding a novel phosphatase, PIR1, phosphatase that interacts with RNA/RNP complex 1. Sequence analysis revealed that the predicted 329-amino acid protein has homology to several dual-specificity phosphatases and contains 2 stretches of arginine-rich sequence similar to those found in some RNA-binding proteins. In vitro, recombinant protein displays protein-tyrosine phosphatase activity and binds directly to RNA.

Molekulargewicht: 22149

NCBI Accession: NP_057448

UniProt: Q9UII6