Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TTBK1 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus und wurde in 1 Publikation erwähnt.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Klon
RB24987
Bindungsspezifität
AA 230-258, N-Term
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TTBK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-258 amino acids from the N-terminal region of human TTBK1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Sato, Xu, Okuyama, Martinez, Walsh, Jacobsen, Swan, Schlautman, Ciborowski, Ikezu: "Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 53, pp. 14511-21, (2009) (PubMed).
Target
TTBK1 (Ttbk1)
(tau Tubulin Kinase 1 (Ttbk1))
Andere Bezeichnung
TTBK1
Hintergrund
TTBK1 is Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.