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TIPIN Antikörper (N-Term)

TIPIN Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB40607 unconjugated
Produktnummer ABIN1881887
  • Target Alle TIPIN Antikörper anzeigen
    TIPIN (TIMELESS Interacting Protein (TIPIN))
    Bindungsspezifität
    • 13
    • 9
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 227-254, N-Term
    Reaktivität
    • 39
    • 9
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 31
    • 8
    Kaninchen
    Klonalität
    • 33
    • 6
    Polyklonal
    Konjugat
    • 27
    • 3
    • 3
    • 2
    • 2
    • 2
    Dieser TIPIN Antikörper ist unkonjugiert
    Applikation
    • 36
    • 20
    • 7
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This TIPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human TIPIN.
    Klon
    RB40607
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TIPIN Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Kemp, Akan, Yilmaz, Grillo, Smith-Roe, Kang, Cordeiro-Stone, Kaufmann, Abraham, Sancar, Unsal-Kaçmaz: "Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16562-71, (2010) (PubMed).

    Leman, Noguchi, Lee, Noguchi: "Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion." in: Journal of cell science, Vol. 123, Issue Pt 5, pp. 660-70, (2010) (PubMed).

    Gotter, Suppa, Emanuel: "Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors." in: Journal of molecular biology, Vol. 366, Issue 1, pp. 36-52, (2007) (PubMed).

  • Target
    TIPIN (TIMELESS Interacting Protein (TIPIN))
    Andere Bezeichnung
    TIPIN (TIPIN Produkte)
    Synonyme
    1110005A05Rik antikoerper, 1110018P21Rik antikoerper, RGD1564084 antikoerper, MGC82649 antikoerper, zgc:91928 antikoerper, tipin antikoerper, TIMELESS interacting protein antikoerper, timeless interacting protein antikoerper, timeless interacting protein S homeolog antikoerper, timeless interacting protein L homeolog antikoerper, TIPIN antikoerper, Tipin antikoerper, tipin.S antikoerper, tipin antikoerper, tipin.L antikoerper
    Hintergrund
    Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.
    Molekulargewicht
    34555
    NCBI Accession
    NP_060328
    UniProt
    Q9BVW5
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