Synaptojanin 2 Antikörper (AA 679-707)

Produktnummer ABIN1881861

Zitiert in 4+ Publikationen. Der Kaninchen Polyklonal anti-Synaptojanin 2 Antikörper (Klon RB41921) (ABIN1881861) detektiert spezifisch Synaptojanin 2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Synaptojanin 2 Antikörper (AA 679-707) (ABIN1881861)

Target: Synaptojanin 2 (SYNJ2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Synaptojanin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB41921

Produktdetails anti-Synaptojanin 2 Antikörper

Bindungsspezifität: AA 679-707

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SYNJ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 679-707 amino acids from the Central region of human SYNJ2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-Synaptojanin 2 Antikörper (ABIN1881861)

Ieguchi, Ueda, Kataoka, Satoh: "Role of the guanine nucleotide exchange factor Ost in negative regulation of receptor endocytosis by the small GTPase Rac1." in: The Journal of biological chemistry, Vol. 282, Issue 32, pp. 23296-305, (2007) (PubMed).

Rossi, Hawthorn, Platt, Burkhardt, Cowell, Ionov: "Identification of inactivating mutations in the JAK1, SYNJ2, and CLPTM1 genes in prostate cancer cells using inhibition of nonsense-mediated decay and microarray analysis." in: Cancer genetics and cytogenetics, Vol. 161, Issue 2, pp. 97-103, (2005) (PubMed).

Chuang, Tran, Rusk, Nakada, Berens, Symons: "Role of synaptojanin 2 in glioma cell migration and invasion." in: Cancer research, Vol. 64, Issue 22, pp. 8271-5, (2004) (PubMed).

Moghadaszadeh, Albrechtsen, Guo, Zaik, Kawaguchi, Borup, Kronqvist, Schroder, Davies, Voit, Nielsen, Engvall, Wewer: "Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins." in: Human molecular genetics, Vol. 12, Issue 19, pp. 2467-79, (2003) (PubMed).

Details zu Synaptojanin 2

Target: Synaptojanin 2 (SYNJ2)

Andere Bezeichnung: SYNJ2

Hintergrund: The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 165538

NCBI Accession: NP_003889

UniProt: O15056

Pathways: Inositol Metabolic Process