Syntaxin 11 Antikörper (N-Term)

Produktnummer ABIN1881853

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Syntaxin 11 in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für Syntaxin 11 Antikörper (N-Term) (ABIN1881853)

Target: Syntaxin 11 (STX11)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Syntaxin 11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB40556

Produktdetails anti-Syntaxin 11 Antikörper

Bindungsspezifität: AA 29-56, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STX11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-56 amino acids from the N-terminal region of human STX11.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-Syntaxin 11 Antikörper (ABIN1881853)

Marsh, Satake, Biroschak, Jacobs, Johnson, Jordan, Bleesing, Filipovich, Zhang: "STX11 mutations and clinical phenotypes of familial hemophagocytic lymphohistiocytosis in North America." in: Pediatric blood & cancer, Vol. 55, Issue 1, pp. 134-40, (2010) (PubMed).

zur Stadt, Rohr, Seifert, Koch, Grieve, Pagel, Strauss, Kasper, Nürnberg, Becker, Maul-Pavicic, Beutel, Janka, Griffiths, Ehl, Hennies: "Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11." in: American journal of human genetics, Vol. 85, Issue 4, pp. 482-92, (2009) (PubMed).

Marcelin, Diatloff-Zito, Nicole, Robert: "Developmental methylation program and concerted expression of Stx11 in mouse tissues." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 20, Issue 3, pp. 131-9, (2009) (PubMed).

Details zu Syntaxin 11

Target: Syntaxin 11 (STX11)

Andere Bezeichnung: STX11

Hintergrund: This gene encodes a member of the syntaxin family. Syntaxins have been implicated in the targeting and fusion of intracellular transport vesicles. This family member may regulate protein transport among late endosomes and the trans-Golgi network. Mutations in this gene have been associated with familial hemophagocytic lymphohistiocytosis.

Molekulargewicht: 33196

NCBI Accession: NP_003755

UniProt: O75558