SIKE1 Antikörper (N-Term)

Produktnummer ABIN1881808

Produktdetails anti-SIKE1 Antikörper

Target: SIKE1 (Suppressor of IKBKE 1 (SIKE1))

Bindungsspezifität: AA 36-63, N-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIKE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.

Klon: RB42417

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-SIKE1 Antikörper (ABIN1881808)

Katayama, Tomaru, Kasukawa, Waki, Nakanishi, Nakamura, Nishida, Yap, Suzuki, Kawai, Suzuki, Carninci, Hayashizaki, Wells, Frith, Ravasi, Pang, Hallinan, Mattick, Hume, Lipovich, Batalov et al.: "Antisense transcription in the mammalian transcriptome...." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1564-6, (2005) (PubMed).

Details zu SIKE1

Target: SIKE1 (Suppressor of IKBKE 1 (SIKE1))

Andere Bezeichnung: Sike1 (SIKE1 Produkte)

Synonyme: SIKE antikoerper, 2810005O12Rik antikoerper, 5730470L24Rik antikoerper, AI450236 antikoerper, AI839862 antikoerper, Sike antikoerper, Sikeb antikoerper, RGD1311316 antikoerper, suppressor of IKBKE 1 antikoerper, SIKE1 antikoerper, Sike1 antikoerper

Hintergrund: Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).

Molekulargewicht: 23522

NCBI Accession: NP_079955

UniProt: Q9CPR7