RXFP1 Antikörper (C-Term)

Produktnummer ABIN1881770

Produktdetails anti-RXFP1 Antikörper

Target: RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))

Bindungsspezifität: AA 685-713, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RXFP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RXFP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 685-713 amino acids from the C-terminal region of human RXFP1.

Klon: RB41815

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-RXFP1 Antikörper (ABIN1881770)

Halls, Cooper: "Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex." in: The EMBO journal, Vol. 29, Issue 16, pp. 2772-87, (2010) (PubMed).

Details zu RXFP1

Target: RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))

Andere Bezeichnung: RXFP1 (RXFP1 Produkte)

Hintergrund: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.

Molekulargewicht: 86975

NCBI Accession: NP_001240657, NP_001240658, NP_067647

UniProt: Q9HBX9

Pathways: Myometrial Relaxation and Contraction