RPL22 Antikörper (C-Term)

Produktnummer ABIN1881759

Dieses Anti-RPL22-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RPL22 in WB. Geeignet für Human und Maus. Dieses Primary Antibody wurde in 5+ Publikationen zitiert.

Kurzübersicht für RPL22 Antikörper (C-Term) (ABIN1881759)

Target: RPL22 (Ribosomal Protein L22 (RPL22))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPL22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB41563

Produktdetails anti-RPL22 Antikörper

Bindungsspezifität: AA 92-121, C-Term

Homologie: C, Pr, Pig, Rat, X

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RPL22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-121 amino acids from the C-terminal region of human RPL22.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:2000. WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-RPL22 Antikörper (ABIN1881759)

Houmani, Davis, Ruf: "Growth-promoting properties of Epstein-Barr virus EBER-1 RNA correlate with ribosomal protein L22 binding." in: Journal of virology, Vol. 83, Issue 19, pp. 9844-53, (2009) (PubMed).

Maggi, Kuchenruether, Dadey, Schwope, Grisendi, Townsend, Pandolfi, Weber: "Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome." in: Molecular and cellular biology, Vol. 28, Issue 23, pp. 7050-65, (2008) (PubMed).

Leonard, Hanke: "A protocol for facial volume restoration with poly-L-lactic acid." in: Journal of drugs in dermatology : JDD, Vol. 5, Issue 9, pp. 872-7, (2006) (PubMed).

Nakao, Mochiki, Nibu, Sugasawa, Uozaki: "Analysis of prognostic factors of nasopharyngeal carcinoma: impact of in situ hybridization for Epstein-Barr virus encoded small RNA 1." in: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, Vol. 134, Issue 4, pp. 639-45, (2006) (PubMed).

Chen, Chiang, Fang: "EBER expression of pure urinary bladder lymphoepithelioma-like carcinoma in two unique Asian patients." in: Urologia internationalis, Vol. 74, Issue 3, pp. 280-2, (2005) (PubMed).

Details zu RPL22

Target: RPL22 (Ribosomal Protein L22 (RPL22))

Andere Bezeichnung: RPL22

Hintergrund: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3,21 translocations, however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2.

Molekulargewicht: 14787

NCBI Accession: NP_000974

UniProt: P35268