PURA Antikörper (C-Term)

Produktnummer ABIN1881707

Der Kaninchen Polyklonal Anti-PURA-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, PURA in Proben von Human zu detektieren. Es sind 5+ Publikationen verfügbar.

Kurzübersicht für PURA Antikörper (C-Term) (ABIN1881707)

Target: PURA (Purine-Rich Element Binding Protein A (PURA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PURA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB20224

Produktdetails anti-PURA Antikörper

Bindungsspezifität: AA 259-287, C-Term

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PURA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the C-terminal region of human PURA.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-PURA Antikörper (ABIN1881707)

Gazla, Carracedo: "Effect of intracellular Wolbachia on interspecific crosses between Drosophila melanogaster and Drosophila simulans." in: Genetics and molecular research : GMR, Vol. 8, Issue 3, pp. 861-9, (2009) (PubMed).

Kaminski, Darbinyan, Merabova, Deshmane, White, Khalili: "Protective role of Puralpha to cisplatin." in: Cancer biology & therapy, Vol. 7, Issue 12, pp. 1926-35, (2009) (PubMed).

Martins-de-Souza, Gattaz, Schmitt, Rewerts, Maccarrone, Dias-Neto, Turck: "Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia." in: European archives of psychiatry and clinical neuroscience, Vol. 259, Issue 3, pp. 151-63, (2009) (PubMed).

Darbinian, Cui, Basile, Del Valle, Otte, Miklossy, Sawaya, Amini, Khalili, Gordon: "Negative regulation of AbetaPP gene expression by pur-alpha." in: Journal of Alzheimer's disease : JAD, Vol. 15, Issue 1, pp. 71-82, (2008) (PubMed).

Wang, Johnson, Kinoshita, Babb, Buckley, Liebes, Melamed, Liu, Kurek, Ossowski, Ferrari: "Androgen receptor overexpression in prostate cancer linked to Pur alpha loss from a novel repressor complex." in: Cancer research, Vol. 68, Issue 8, pp. 2678-88, (2008) (PubMed).

Details zu PURA

Target: PURA (Purine-Rich Element Binding Protein A (PURA))

Andere Bezeichnung: PURA

Hintergrund: This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Molekulargewicht: 34911

NCBI Accession: NP_005850

UniProt: Q00577