PDCD6 Antikörper (N-Term)

Produktnummer ABIN1881643

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PDCD6 in WB. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 4+ Publikationen zitiert.

Kurzübersicht für PDCD6 Antikörper (N-Term) (ABIN1881643)

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDCD6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB41816

Produktdetails anti-PDCD6 Antikörper

Bindungsspezifität: AA 19-47, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PDCD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of human PDCD6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-PDCD6 Antikörper (ABIN1881643)

Vergarajauregui, Martina, Puertollano: "Identification of the penta-EF-hand protein ALG-2 as a Ca2+-dependent interactor of mucolipin-1." in: The Journal of biological chemistry, Vol. 284, Issue 52, pp. 36357-66, (2009) (PubMed).

Okumura, Ichioka, Kobayashi, Suzuki, Yoshida, Shibata, Maki: "Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101." in: Biochemical and biophysical research communications, Vol. 386, Issue 1, pp. 237-41, (2009) (PubMed).

Abe, Miyakushi, Nagai, Norimatsu: "Study of the factors affecting the photoelectrode characteristics of a perylene/phthalocyanine bilayer working in the water phase." in: Physical chemistry chemical physics : PCCP, Vol. 10, Issue 11, pp. 1562-8, (2008) (PubMed).

Yamada, Arao, Gotoda, Taniguchi, Oda, Shirao, Shimada, Hamaguchi, Kato, Hamano, Koizumi, Tamura, Saito, Shimoda, Saka, Fukagawa, Katai, Sano, Sasako, Nishio: "Identification of prognostic biomarkers in gastric cancer using endoscopic biopsy samples." in: Cancer science, Vol. 99, Issue 11, pp. 2193-9, (2008) (PubMed).

Details zu PDCD6

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Andere Bezeichnung: PDCD6

Hintergrund: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.

Molekulargewicht: 21868

NCBI Accession: NP_001254485, NP_001254486, NP_001254487, NP_001254488, NP_037364

UniProt: O75340

Pathways: Positive Regulation of Endopeptidase Activity