MAK Antikörper (C-Term)

Produktnummer ABIN1881520

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MAK in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 5+ Publikationen erwähnt.

Kurzübersicht für MAK Antikörper (C-Term) (ABIN1881520)

Target: MAK (Male Germ Cell-Associated Kinase (MAK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB42425

Produktdetails anti-MAK Antikörper

Bindungsspezifität: AA 595-623, C-Term

Homologie: M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 595-623 amino acids from the C-terminal region of human MAK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-MAK Antikörper (ABIN1881520)

Ma, Xia, Desai, Boucher, Guan, Shih, Shi, deVere White, Chen, Tepper, Kung: "Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells." in: Cancer research, Vol. 66, Issue 17, pp. 8439-47, (2006) (PubMed).

Fu, Larson, Chitta, Parker, Turk, Lawrence, Kaldis, Galaktionov, Cohn, Shabanowitz, Hunt, Sturgill: "Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase." in: Molecular and cellular biology, Vol. 26, Issue 22, pp. 8639-54, (2006) (PubMed).

Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).

Xia, Robinson, Ma, Chen, Wu, Qiu, Kung: "Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells." in: The Journal of biological chemistry, Vol. 277, Issue 38, pp. 35422-33, (2002) (PubMed).

Woodle, Newman, Cohen: "Sterically stabilized liposomes: physical and biological properties." in: Journal of drug targeting, Vol. 2, Issue 5, pp. 397-403, (1995) (PubMed).

Details zu MAK

Target: MAK (Male Germ Cell-Associated Kinase (MAK))

Andere Bezeichnung: MAK

Hintergrund: The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.

Molekulargewicht: 70581

NCBI Accession: NP_001229314, NP_001229886, NP_005897

UniProt: P20794