CCKAR Antikörper (C-Term)

Produktnummer ABIN1881514

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CCKAR in WB. Er zeigt eine Reaktivität gegenüber Maus und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für CCKAR Antikörper (C-Term) (ABIN1881514)

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCKAR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CCKAR Antikörper

Bindungsspezifität: AA 325-356, C-Term

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Cckar antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-356 amino acids from the C-terminal region of mouse Cckar.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-CCKAR Antikörper (ABIN1881514)

Lacourse, Lay, Swanberg, Jenkins, Samuelson: "Molecular structure of the mouse CCK-A receptor gene." in: Biochemical and biophysical research communications, Vol. 236, Issue 3, pp. 630-5, (1997) (PubMed).

Takata, Takiguchi, Kataoka, Funakoshi, Miyasaka, Kono: "Mouse cholecystokinin type-A receptor gene and its structural analysis." in: Gene, Vol. 187, Issue 2, pp. 267-71, (1997) (PubMed).

Details zu CCKAR

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Andere Bezeichnung: Cckar

Hintergrund: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).

Molekulargewicht: 48437

NCBI Accession: NP_033957

UniProt: O08786

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Feeding Behaviour