Der Kaninchen Polyklonal Anti-Lrig1-Antikörper wurde für WB validiert. Er ist geeignet, Lrig1 in Proben von Maus zu detektieren. Es ist 1 Publikation verfügbar.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This LRIG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 801-829 amino acids from the C-terminal region of human LRIG1.
Lrig1
Reaktivität: Human, Maus, Ratte
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 594
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Ye, Gao, Xu, Zeng, Ou, Mao, Wang, He, Wang, Yang, Guo, Lei: "Upregulation of LRIG1 suppresses malignant glioma cell growth by attenuating EGFR activity." in: Journal of neuro-oncology, Vol. 94, Issue 2, pp. 183-94, (2009) (PubMed).
Target
Lrig1
(Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))
Andere Bezeichnung
LRIG1
Hintergrund
LRIG1 act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.