LHX4 Antikörper (AA 133-161)

Produktnummer ABIN1881496

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LHX4 in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für LHX4 Antikörper (AA 133-161) (ABIN1881496)

Target: LHX4 (LIM Homeobox 4 (LHX4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LHX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB30670

Produktdetails anti-LHX4 Antikörper

Bindungsspezifität: AA 133-161

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LHX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-161 amino acids from the Central region of human LHX4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-LHX4 Antikörper (ABIN1881496)

Castinetti, Saveanu, Reynaud, Quentien, Buffin, Brauner, Kaffel, Albarel, Guedj, El Kholy, Amin, Enjalbert, Barlier, Brue: "A novel dysfunctional LHX4 mutation with high phenotypical variability in patients with hypopituitarism." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 7, pp. 2790-9, (2008) (PubMed).

de Bruijn, van Dijk, Willemse, van Kessel: "The C terminus of the synovial sarcoma-associated SSX proteins interacts with the LIM homeobox protein LHX4." in: Oncogene, Vol. 27, Issue 5, pp. 653-62, (2008) (PubMed).

Pfaeffle, Hunter, Savage, Duran-Prado, Mullen, Neeb, Eiholzer, Hesse, Haddad, Stobbe, Blum, Weigel, Rhodes: "Three novel missense mutations within the LHX4 gene are associated with variable pituitary hormone deficiencies." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 3, pp. 1062-71, (2008) (PubMed).

Liu, Luo, Liu, McNeilly, Cui: "Specificity protein 1 (Sp1) plays role in regulating LIM homeodomain transcription factor Lhx4 gene expression." in: Biochemical and biophysical research communications, Vol. 366, Issue 1, pp. 36-41, (2007) (PubMed).

Details zu LHX4

Target: LHX4 (LIM Homeobox 4 (LHX4))

Andere Bezeichnung: LHX4

Hintergrund: This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of the pituitary gland. Mutations in this gene are associated with syndromic short stature and pituitary and hindbrain defects. An alternative splice variant has been described but its biological nature has not been determined.

Molekulargewicht: 43124

NCBI Accession: NP_203129

UniProt: Q969G2