Keratin 72 Antikörper (AA 313-342)

Produktnummer ABIN1881487

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Keratin 72 in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für Keratin 72 Antikörper (AA 313-342) (ABIN1881487)

Target: Keratin 72 (KRT72)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Keratin 72 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB40960

Produktdetails anti-Keratin 72 Antikörper

Bindungsspezifität: AA 313-342

Homologie: B

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KRT72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-342 amino acids from the Central region of human KRT72.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-Keratin 72 Antikörper (ABIN1881487)

Langbein, Rogers, Praetzel, Winter, Schweizer: "K6irs1, K6irs2, K6irs3, and K6irs4 represent the inner-root-sheath-specific type II epithelial keratins of the human hair follicle." in: The Journal of investigative dermatology, Vol. 120, Issue 4, pp. 512-22, (2003) (PubMed).

Porter, Corden, Lunny, Smith, Lane, McLean: "Keratin K6irs is specific to the inner root sheath of hair follicles in mice and humans." in: The British journal of dermatology, Vol. 145, Issue 4, pp. 558-68, (2001) (PubMed).

Details zu Keratin 72

Target: Keratin 72 (KRT72)

Andere Bezeichnung: KRT72

Hintergrund: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 55877

NCBI Accession: NP_001139697, NP_001139698, NP_542785

UniProt: Q14CN4