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KISS1R Antikörper (AA 235-263)

Dieses Anti-KISS1R-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KISS1R in WB. Geeignet für Human.
Produktnummer ABIN1881480

Kurzübersicht für KISS1R Antikörper (AA 235-263) (ABIN1881480)

Target

Alle KISS1R Antikörper anzeigen
KISS1R (KISS1 Receptor (KISS1R))

Reaktivität

  • 50
  • 35
  • 34
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 63
  • 12
Kaninchen

Klonalität

  • 63
  • 12
Polyklonal

Konjugat

  • 47
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser KISS1R Antikörper ist unkonjugiert

Applikation

  • 46
  • 32
  • 24
  • 23
  • 13
  • 13
  • 6
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB)

Klon

RB40407
  • Bindungsspezifität

    • 12
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 235-263

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This KISS1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the Central region of human KISS1R.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Haltbarkeit

    6 months
  • Target

    KISS1R (KISS1 Receptor (KISS1R))

    Andere Bezeichnung

    KISS1R

    Hintergrund

    Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

    Molekulargewicht

    42586

    NCBI Accession

    NP_115940

    UniProt

    Q969F8
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