ICT1 Antikörper (C-Term)

Produktnummer ABIN1881444

Dieses Anti-ICT1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ICT1 in WB und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 5+ Publikationen zitiert.

Kurzübersicht für ICT1 Antikörper (C-Term) (ABIN1881444)

Target: ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ICT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB42881

Produktdetails anti-ICT1 Antikörper

Bindungsspezifität: AA 153-179, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ICT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-179 amino acids from the C-terminal region of human ICT1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ICT1 Antikörper (ABIN1881444)

Wang, He, Zhang, Yang, Wang, Liu, Wu: "Knockdown of Immature Colon Carcinoma Transcript 1 Inhibits Proliferation and Promotes Apoptosis of Non-Small Cell Lung Cancer Cells." in: Technology in cancer research & treatment, Vol. 16, Issue 5, pp. 559-569, (2018) (PubMed).

Tao, Song, Han, Wang, Zhao, Gu: "miR-205 regulation of ICT1 has an oncogenic potential via promoting the migration and invasion of gastric cancer cells." in: Biomedicine & pharmacotherapy, Vol. 96, pp. 191-197, (2018) (PubMed).

Wang, Jin, Wu, Wang, Li: "Immature colon carcinoma transcript-1 promotes proliferation of gastric cancer cells." in: Acta biochimica et biophysica Sinica, Vol. 49, Issue 11, pp. 979-988, (2018) (PubMed).

Chang, Yu, Tian, Lin: "Immature colon carcinoma transcript-1 promotes cell growth of hepatocellular carcinoma via facilitating cell cycle progression and apoptosis resistance." in: Oncology reports, Vol. 38, Issue 6, pp. 3489-3496, (2018) (PubMed).

Xie, Zhang, Shen, Cao, Gu, Che: "Knockdown of immature colon carcinoma transcript-1 inhibits proliferation of glioblastoma multiforme cells through Gap 2/mitotic phase arrest." in: OncoTargets and therapy, Vol. 8, pp. 1119-27, (2015) (PubMed).

Details zu ICT1

Target: ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

Andere Bezeichnung: ICT1

Hintergrund: Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.

Molekulargewicht: 23630

NCBI Accession: NP_001536

UniProt: Q14197