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HPS5 Antikörper (N-Term)

HPS5 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB42226 unconjugated
Produktnummer ABIN1881436
  • Target Alle HPS5 Antikörper anzeigen
    HPS5 (Hermansky-Pudlak Syndrome 5 (HPS5))
    Bindungsspezifität
    • 15
    • 13
    • 6
    AA 88-116, N-Term
    Reaktivität
    • 16
    • 15
    • 1
    Human
    Wirt
    • 30
    Kaninchen
    Klonalität
    • 30
    Polyklonal
    Konjugat
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HPS5 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 17
    • 13
    • 13
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This HPS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the N-terminal region of human HPS5.
    Klon
    RB42226
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Helip-Wooley, Westbroek, Dorward, Koshoffer, Huizing, Boissy, Gahl: "Improper trafficking of melanocyte-specific proteins in Hermansky-Pudlak syndrome type-5." in: The Journal of investigative dermatology, Vol. 127, Issue 6, pp. 1471-8, (2007) (PubMed).

    Huizing, Parkes, Helip-Wooley, White, Gahl: "Platelet alpha granules in BLOC-2 and BLOC-3 subtypes of Hermansky-Pudlak syndrome." in: Platelets, Vol. 18, Issue 2, pp. 150-7, (2007) (PubMed).

    Matsuoka, Ballif, Smogorzewska, McDonald, Hurov, Luo, Bakalarski, Zhao, Solimini, Lerenthal, Shiloh, Gygi, Elledge: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, (2007) (PubMed).

    Huizing, Hess, Dorward, Claassen, Helip-Wooley, Kleta, Kaiser-Kupfer, White, Gahl: "Cellular, molecular and clinical characterization of patients with Hermansky-Pudlak syndrome type 5." in: Traffic (Copenhagen, Denmark), Vol. 5, Issue 9, pp. 711-22, (2004) (PubMed).

    Di Pietro, Falcón-Pérez, DellAngelica: "Characterization of BLOC-2, a complex containing the Hermansky-Pudlak syndrome proteins HPS3, HPS5 and HPS6." in: Traffic (Copenhagen, Denmark), Vol. 5, Issue 4, pp. 276-83, (2004) (PubMed).

  • Target
    HPS5 (Hermansky-Pudlak Syndrome 5 (HPS5))
    Andere Bezeichnung
    HPS5 (HPS5 Produkte)
    Synonyme
    AIBP63 antikoerper, Aa2-028 antikoerper, Ab1-018 antikoerper, zgc:162420 antikoerper, AI646796 antikoerper, AL022647 antikoerper, C85120 antikoerper, haze antikoerper, hz antikoerper, maroon antikoerper, mr antikoerper, ru-2 antikoerper, ru2 antikoerper, HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 antikoerper, Hermansky-Pudlak syndrome 5 antikoerper, HPS5 antikoerper, Hps5 antikoerper, hps5 antikoerper
    Hintergrund
    This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.
    Molekulargewicht
    127449
    NCBI Accession
    NP_009147, NP_852608, NP_852609
    UniProt
    Q9UPZ3
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