HOXA10 Antikörper (AA 252-281)

Produktnummer ABIN1881425

Der Kaninchen Polyklonal Anti-HOXA10-Antikörper wurde für WB validiert. Er ist geeignet, HOXA10 in Proben von Maus zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für HOXA10 Antikörper (AA 252-281) (ABIN1881425)

Target: HOXA10 (Homeobox A10 (HOXA10))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXA10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB39509

Produktdetails anti-HOXA10 Antikörper

Bindungsspezifität: AA 252-281

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Hoxa10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from the Central region of mouse Hoxa10.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-HOXA10 Antikörper (ABIN1881425)

Gordon, Hassan, Saini, Montecino, van Wijnen, Stein, Stein, Lian: "Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors." in: Molecular and cellular biology, Vol. 30, Issue 14, pp. 3531-41, (2010) (PubMed).

Das: "Regional development of uterine decidualization: molecular signaling by Hoxa-10." in: Molecular reproduction and development, Vol. 77, Issue 5, pp. 387-96, (2010) (PubMed).

Vinagre, Moncaut, Carapuço, Nóvoa, Bom, Mallo: "Evidence for a myotomal Hox/Myf cascade governing nonautonomous control of rib specification within global vertebral domains." in: Developmental cell, Vol. 18, Issue 4, pp. 655-61, (2010) (PubMed).

Details zu HOXA10

Target: HOXA10 (Homeobox A10 (HOXA10))

Andere Bezeichnung: Hoxa10

Hintergrund: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of a cluster on chromosome 6 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants encoding different isoforms have been described.

Molekulargewicht: 43292

NCBI Accession: NP_001116422, NP_032289

UniProt: P31310