HNRNPH1 Antikörper (N-Term)

Produktnummer ABIN1881424

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HNRNPH1 in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für HNRNPH1 Antikörper (N-Term) (ABIN1881424)

Target: HNRNPH1 (Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB42336

Produktdetails anti-HNRNPH1 Antikörper

Bindungsspezifität: AA 48-77, N-Term

Homologie: M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HNRNPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human HNRNPH1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-HNRNPH1 Antikörper (ABIN1881424)

Van Dusen, Yee, McNally, McNally: "A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1." in: Molecular and cellular biology, Vol. 30, Issue 10, pp. 2552-62, (2010) (PubMed).

Rauch, ONeill, Mack, Matthias, Munz, Kolch, Gires: "Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcription." in: Cancer research, Vol. 70, Issue 4, pp. 1679-88, (2010) (PubMed).

Fisette, Toutant, Dugré-Brisson, Desgroseillers, Chabot: "hnRNP A1 and hnRNP H can collaborate to modulate 5' splice site selection." in: RNA (New York, N.Y.), Vol. 16, Issue 1, pp. 228-38, (2009) (PubMed).

Details zu HNRNPH1

Target: HNRNPH1 (Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1))

Andere Bezeichnung: HNRNPH1

Hintergrund: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype. [provided by RefSeq].

Molekulargewicht: 49229

NCBI Accession: NP_001244222, NP_005511

UniProt: P31943