HIST2H2AC Antikörper (AA 18-46)

Produktnummer ABIN1881417

Dieses Anti-HIST2H2AC-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HIST2H2AC in WB. Geeignet für Human. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für HIST2H2AC Antikörper (AA 18-46) (ABIN1881417)

Target: HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIST2H2AC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB41799

Produktdetails anti-HIST2H2AC Antikörper

Bindungsspezifität: AA 18-46

Homologie: Rat, B, X, M, C, Pr, Zf, D

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-HIST2H2AC Antikörper (ABIN1881417)

Ishibashi, Dryhurst, Rose, Shabanowitz, Hunt, Ausió: "Acetylation of vertebrate H2A.Z and its effect on the structure of the nucleosome." in: Biochemistry, Vol. 48, Issue 22, pp. 5007-17, (2009) (PubMed).

Karaczyn, Cheng, Buzard, Hartley, Esposito, Kasprzak: "Truncation of histone H2A's C-terminal tail, as is typical for Ni(II)-assisted specific peptide bond hydrolysis, has gene expression altering effects." in: Annals of clinical and laboratory science, Vol. 39, Issue 3, pp. 251-62, (2009) (PubMed).

Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." in: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).

Details zu HIST2H2AC

Target: HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))

Andere Bezeichnung: HIST2H2AC

Hintergrund: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.

Molekulargewicht: 13988

NCBI Accession: NP_003508

UniProt: Q16777