HIST1H3/2H3/3H3/H3F3 (AA 28-57), (N-Term) Antikörper

Produktnummer ABIN1881415

Produktdetails

Target: HIST1H3/2H3/3H3/H3F3

Bindungsspezifität: AA 28-57, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, M, Rat, C, Zf, X, E, D, Pig, Rb

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HIST1H3/2H3/3H3/H3F3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-57 amino acids from the N-terminal region of human HIST1H3/2H3/3H3/H3F3.

Klon: RB42493

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Antigendetails

Target: HIST1H3/2H3/3H3/H3F3

Hintergrund: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Molekulargewicht: 15404

NCBI Accession: NP_003520, NP_003521, NP_003522, NP_003523, NP_003524, NP_003525, NP_003526, NP_003527, NP_003528, NP_066298

UniProt: P68431