GSTP1 Antikörper (AA 97-126)

Produktnummer ABIN1881393

Dieses Anti-GSTP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GSTP1 in WB, IF, FACS und IHC (p). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für GSTP1 Antikörper (AA 97-126) (ABIN1881393)

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB20807

Produktdetails anti-GSTP1 Antikörper

Bindungsspezifität: AA 97-126

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GSTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human GSTP1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50. IHC: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-GSTP1 Antikörper (ABIN1881393)

Cho, Eom, Kim, Kim, Lee, Kong: "Glutathione-S-transferase genotypes influence the risk of chemotherapy-related toxicities and prognosis in Korean patients with diffuse large B-cell lymphoma." in: Cancer genetics and cytogenetics, Vol. 198, Issue 1, pp. 40-6, (2010) (PubMed).

Kanai, Yoshioka, Tanaka, Nagayama, Matsumoto, Nishimura, Niimi, Teramukai, Takahashi, Mori, Kitano, Ishiguro, Yanagihara, Chiba, Fukushima, Matsuda: "Associations between glutathione S-transferase pi Ile105Val and glyoxylate aminotransferase Pro11Leu and Ile340Met polymorphisms and early-onset oxaliplatin-induced neuropathy." in: Cancer epidemiology, Vol. 34, Issue 2, pp. 189-93, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Details zu GSTP1

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Andere Bezeichnung: GSTP1

Hintergrund: Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Molekulargewicht: 23356

NCBI Accession: NP_000843

UniProt: P09211

Pathways: Cellular Response to Molecule of Bacterial Origin