Nucleostemin Antikörper (C-Term)

Produktnummer ABIN1881380

Der Kaninchen Polyklonal Anti-Nucleostemin-Antikörper wurde für WB validiert. Er ist geeignet, Nucleostemin in Proben von Maus zu detektieren. Es sind 5+ Publikationen verfügbar.

Kurzübersicht für Nucleostemin Antikörper (C-Term) (ABIN1881380)

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nucleostemin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB40720

Produktdetails anti-Nucleostemin Antikörper

Bindungsspezifität: AA 442-471, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Gnl3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-471 amino acids from the C-terminal region of mouse Gnl3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-Nucleostemin Antikörper (ABIN1881380)

Hirai, Romanova, Kellner, Verma, Rayner, Asakura, Kikyo: "Post-mitotic role of nucleostemin as a promoter of skeletal muscle cell differentiation." in: Biochemical and biophysical research communications, Vol. 391, Issue 1, pp. 299-304, (2010) (PubMed).

Tamase, Muraguchi, Naka, Tanaka, Kinoshita, Hoshii, Ohmura, Shugo, Ooshio, Nakada, Sawamoto, Onodera, Matsumoto, Oshima, Asano, Saya, Okano, Suda, Hamada, Hirao: "Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 40, pp. 17163-8, (2009) (PubMed).

Nomura, Maruyama, Katano, Kato, Zhang, Masui, Mizuno, Okazaki, Nishimoto, Okuda: "Differential requirement for nucleostemin in embryonic stem cell and neural stem cell viability." in: Stem cells (Dayton, Ohio), Vol. 27, Issue 5, pp. 1066-76, (2009) (PubMed).

Ohmura, Naka, Hoshii, Muraguchi, Shugo, Tamase, Uema, Ooshio, Arai, Takubo, Nagamatsu, Hamaguchi, Takagi, Ishihara, Sakurada, Miyaji, Suda, Hirao: "Identification of stem cells during prepubertal spermatogenesis via monitoring of nucleostemin promoter activity." in: Stem cells (Dayton, Ohio), Vol. 26, Issue 12, pp. 3237-46, (2008) (PubMed).

Siddiqi, Gude, Hosoda, Muraski, Rubio, Emmanuel, Fransioli, Vitale, Parolin, DAmario, Schaefer, Kajstura, Leri, Anversa, Sussman: "Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge." in: Circulation research, Vol. 103, Issue 1, pp. 89-97, (2008) (PubMed).

Details zu Nucleostemin

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Andere Bezeichnung: Gnl3

Hintergrund: Gnl3 may be required to maintain the proliferative capacity of stem cells (By similarity).

Molekulargewicht: 60786

NCBI Accession: NP_705775

UniProt: Q8CI11