GLUD2 Antikörper (N-Term)

Produktnummer ABIN1881376

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GLUD2 in WB. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für GLUD2 Antikörper (N-Term) (ABIN1881376)

Target: GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLUD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB42527

Produktdetails anti-GLUD2 Antikörper

Bindungsspezifität: AA 75-103, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GLUD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-103 amino acids from the N-terminal region of human GLUD2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-GLUD2 Antikörper (ABIN1881376)

Spanaki, Zaganas, Kleopa, Plaitakis: "Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supporting cells." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16748-56, (2010) (PubMed).

Plaitakis, Latsoudis, Kanavouras, Ritz, Bronstein, Skoula, Mastorodemos, Papapetropoulos, Borompokas, Zaganas, Xiromerisiou, Hadjigeorgiou, Spanaki: "Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset." in: European journal of human genetics : EJHG, Vol. 18, Issue 3, pp. 336-41, (2010) (PubMed).

Details zu GLUD2

Target: GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))

Andere Bezeichnung: GLUD2

Hintergrund: The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.

Molekulargewicht: 61434

NCBI Accession: NP_036216

UniProt: P49448

Pathways: Synaptic Membrane