GGT1 Antikörper (N-Term)

Produktnummer ABIN1881373

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GGT1 in WB. Er zeigt eine Reaktivität gegenüber Human und Maus und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für GGT1 Antikörper (N-Term) (ABIN1881373)

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GGT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB41020

Produktdetails anti-GGT1 Antikörper

Bindungsspezifität: AA 124-152, N-Term

Homologie: Pig, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of human GGT1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-GGT1 Antikörper (ABIN1881373)

Ikeda, Maki, Yin, Kawate, Adachi, Ohnaka, Takayanagi, Kono: "Relation of coffee consumption and serum liver enzymes in Japanese men and women with reference to effect modification of alcohol use and body mass index." in: Scandinavian journal of clinical and laboratory investigation, Vol. 70, Issue 3, pp. 171-9, (2010) (PubMed).

Fujita, Ueno, Hata: "Association of gamma-glutamyltransferase with incidence of type 2 diabetes in Japan." in: Experimental biology and medicine (Maywood, N.J.), Vol. 235, Issue 3, pp. 335-41, (2010) (PubMed).

Speliotes, Butler, Palmer, Voight, Hirschhorn: "PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease." in: Hepatology (Baltimore, Md.), Vol. 52, Issue 3, pp. 904-12, (2010) (PubMed).

Kamatani, Matsuda, Okada, Kubo, Hosono, Daigo, Nakamura, Kamatani: "Genome-wide association study of hematological and biochemical traits in a Japanese population." in: Nature genetics, Vol. 42, Issue 3, pp. 210-5, (2010) (PubMed).

Details zu GGT1

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Andere Bezeichnung: GGT1

Hintergrund: The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molekulargewicht: 61410

NCBI Accession: NP_001027536, NP_001027537, NP_005256, NP_038347

UniProt: P19440