GEMIN4 Antikörper (N-Term)

Produktnummer ABIN1881369

Dieses Anti-GEMIN4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GEMIN4 in WB. Geeignet für Human. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für GEMIN4 Antikörper (N-Term) (ABIN1881369)

Target: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GEMIN4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB41821

Produktdetails anti-GEMIN4 Antikörper

Bindungsspezifität: AA 273-301, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GEMIN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the N-terminal region of human GEMIN4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-GEMIN4 Antikörper (ABIN1881369)

Clague, Lippman, Yang, Hildebrandt, Ye, Lee, Wu: "Genetic variation in MicroRNA genes and risk of oral premalignant lesions." in: Molecular carcinogenesis, Vol. 49, Issue 2, pp. 183-9, (2010) (PubMed).

Kim, Choi, Jin, Kang, Choi, Jeon, Lee, Kim, Kim, Kim, Son, Jung, Park: "Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study." in: Molecular carcinogenesis, Vol. 49, Issue 10, pp. 913-21, (2010) (PubMed).

Wilker, Baccarelli, Suh, Vokonas, Wright, Schwartz: "Black carbon exposures, blood pressure, and interactions with single nucleotide polymorphisms in MicroRNA processing genes." in: Environmental health perspectives, Vol. 118, Issue 7, pp. 943-8, (2010) (PubMed).

Ye, Wang, Gu, Yang, Lin, Ajani, Wu: "Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk." in: Cancer prevention research (Philadelphia, Pa.), Vol. 1, Issue 6, pp. 460-9, (2009) (PubMed).

Details zu GEMIN4

Target: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Andere Bezeichnung: GEMIN4

Hintergrund: The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Molekulargewicht: 120037

NCBI Accession: NP_056536

UniProt: P57678

Pathways: Ribonucleoprotein Complex Subunit Organization