GDI1 Antikörper (C-Term)

Produktnummer ABIN1881368

Der Kaninchen Polyklonal Anti-GDI1-Antikörper wurde für WB validiert. Er ist geeignet, GDI1 in Proben von Human, Maus und Ratte zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für GDI1 Antikörper (C-Term) (ABIN1881368)

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB42409

Produktdetails anti-GDI1 Antikörper

Bindungsspezifität: AA 415-443, C-Term

Homologie: B, Pr

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GDI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the C-terminal region of human GDI1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-GDI1 Antikörper (ABIN1881368)

Massignan, Biasini, Lauranzano, Veglianese, Pignataro, Fioriti, Harris, Salmona, Chiesa, Bonetto: "Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor alpha (GDI)/Rab11 pathway." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 4, pp. 611-22, (2010) (PubMed).

Martins-de-Souza, Schmitt, Röder, Lebar, Schneider-Axmann, Falkai, Turck: "Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia." in: Journal of psychiatric research, Vol. 44, Issue 14, pp. 989-91, (2010) (PubMed).

Chen, Deng, Zhang, Yang, Xie, Xu: "GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation." in: The Biochemical journal, Vol. 422, Issue 2, pp. 229-35, (2009) (PubMed).

Zhang, DU, Zheng, Gao, Huang, Li, Chen, Zhang: "[Relationship between the polymorphisms of GDI1, children NSMR and their intelligence in Qinba region]." in: Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji, Vol. 30, Issue 5, pp. 590-4, (2008) (PubMed).

Details zu GDI1

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Andere Bezeichnung: GDI1

Hintergrund: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.

Molekulargewicht: 50583

NCBI Accession: NP_001484

UniProt: P31150