FMO5 Antikörper (C-Term)

Produktnummer ABIN1881348

Dieses Anti-FMO5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FMO5 in WB. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für FMO5 Antikörper (C-Term) (ABIN1881348)

Target: FMO5 (Flavin Containing Monooxygenase 5 (FMO5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FMO5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB42789

Produktdetails anti-FMO5 Antikörper

Bindungsspezifität: AA 474-502, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FMO5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-502 amino acids from the C-terminal region of human FMO5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-FMO5 Antikörper (ABIN1881348)

Ross, Katzov-Eckert, Dubé, Brooks, Rassekh, Barhdadi, Feroz-Zada, Visscher, Brown, Rieder, Rogers, Phillips, Carleton, Hayden: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." in: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).

Furnes, Feng, Sommer, Schlenk: "Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 31, Issue 2, pp. 187-93, (2003) (PubMed).

Details zu FMO5

Target: FMO5 (Flavin Containing Monooxygenase 5 (FMO5))

Andere Bezeichnung: FMO5

Hintergrund: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 60221

NCBI Accession: NP_001138301, NP_001138302, NP_001452

UniProt: P49326