This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This FBXO43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 668-694 amino acids from the C-terminal region of human FBXO43.
FBXO43
Reaktivität: Human
WB, IF, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Target
FBXO43
(F-Box Protein 43 (FBXO43))
Andere Bezeichnung
FBXO43
Hintergrund
Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation (Probable).