EFNB2A Antikörper (AA 163-194)

Produktnummer ABIN1881282

Dieses Anti-EFNB2A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EFNB2A in WB. Geeignet für Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für EFNB2A Antikörper (AA 163-194) (ABIN1881282)

Target: EFNB2A

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EFNB2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EFNB2A Antikörper

Bindungsspezifität: AA 163-194

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DANRE efnb2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-194 amino acids from the Central region of DANRE efnb2a.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-EFNB2A Antikörper (ABIN1881282)

Chan, Mably, Serluca, Chen, Goldstein, Thomas, Cleary, Brennan, Fishman, Roberts: "Morphogenesis of prechordal plate and notochord requires intact Eph/ephrin B signaling." in: Developmental biology, Vol. 234, Issue 2, pp. 470-82, (2001) (PubMed).

Durbin, Brennan, Shiomi, Cooke, Barrios, Shanmugalingam, Guthrie, Lindberg, Holder: "Eph signaling is required for segmentation and differentiation of the somites." in: Genes & development, Vol. 12, Issue 19, pp. 3096-109, (1998) (PubMed).

Details zu EFNB2A

Target: EFNB2A

Hintergrund: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with ephb4 may play a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration (By similarity).

Molekulargewicht: 36724

NCBI Accession: NP_571098

UniProt: O73874