DPEP1 Antikörper (N-Term)

Produktnummer ABIN1881269

Der Kaninchen Polyklonal Anti-DPEP1-Antikörper wurde für WB validiert. Er ist geeignet, DPEP1 in Proben von Human zu detektieren.

Kurzübersicht für DPEP1 Antikörper (N-Term) (ABIN1881269)

Target: DPEP1 (Dipeptidase 1 (Renal) (DPEP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPEP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB41566

Produktdetails anti-DPEP1 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DPEP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DPEP1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu DPEP1

Target: DPEP1 (Dipeptidase 1 (Renal) (DPEP1))

Andere Bezeichnung: DPEP1

Hintergrund: DPEP1 (EC 3.4.13.11) is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates, e.g., leukotriene D4 (Kozak and Tate, 1982 [PubMed 6122685]). DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem (Campbell et al., 1984 [PubMed 6334084]). Earlier, beta-lactamase enzymes were thought to occur only in bacteria, where their probable function was in protecting the organisms against the action of beta-lactam antibiotics. These antibiotics exhibit selective toxicity against bacteria but virtual inertness against many eukaryotic cells (Adachi et al., 1990 [PubMed 2303490]).

Molekulargewicht: 45674

NCBI Accession: NP_001121613, NP_004404

UniProt: P16444

Pathways: Inositol Metabolic Process