CRYM Antikörper (AA 154-183)

Produktnummer ABIN1881230

Produktdetails anti-CRYM Antikörper

Target: CRYM (Crystallin, mu (CRYM))

Bindungsspezifität: AA 154-183

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRYM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CRYM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the Central region of human CRYM.

Klon: RB40546

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-CRYM Antikörper (ABIN1881230)

Al-Kafaji, Malik: "Hyperglycemia induces elevated expression of thyroid hormone binding protein in vivo in kidney and heart and in vitro in mesangial cells." in: Biochemical and biophysical research communications, Vol. 391, Issue 4, pp. 1585-91, (2010) (PubMed).

Malinowska, Cavarretta, Susani, Wrulich, Uberall, Kenner, Culig: "Identification of mu-crystallin as an androgen-regulated gene in human prostate cancer." in: The Prostate, Vol. 69, Issue 10, pp. 1109-18, (2009) (PubMed).

Martins-de-Souza, Gattaz, Schmitt, Maccarrone, Hunyadi-Gulyás, Eberlin, Souza, Marangoni, Novello, Turck, Dias-Neto: "Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia." in: Journal of psychiatric research, Vol. 43, Issue 11, pp. 978-86, (2009) (PubMed).

Martins-de-Souza, Gattaz, Schmitt, Rewerts, Maccarrone, Dias-Neto, Turck: "Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia." in: European archives of psychiatry and clinical neuroscience, Vol. 259, Issue 3, pp. 151-63, (2009) (PubMed).

Details zu CRYM

Target: CRYM (Crystallin, mu (CRYM))

Andere Bezeichnung: CRYM (CRYM Produkte)

Hintergrund: Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene.

Molekulargewicht: 33776

NCBI Accession: NP_001014444, NP_001879

UniProt: Q14894

Pathways: Hormone Transport, Sensory Perception of Sound