COPG Antikörper (C-Term)

Produktnummer ABIN1881223

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch COPG in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für COPG Antikörper (C-Term) (ABIN1881223)

Target: COPG (Coatomer Protein Complex, Subunit gamma (COPG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COPG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB41787

Produktdetails anti-COPG Antikörper

Bindungsspezifität: AA 721-750, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This COPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 721-750 amino acids from the C-terminal region of human COPG.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-COPG Antikörper (ABIN1881223)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Rohde, Cheong, Konrad, Paiha, Mayinger, Boehmelt: "The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52689-99, (2003) (PubMed).

Details zu COPG

Target: COPG (Coatomer Protein Complex, Subunit gamma (COPG))

Andere Bezeichnung: COPG

Hintergrund: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).

Molekulargewicht: 97718

NCBI Accession: NP_057212

UniProt: Q9Y678