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COPG Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch COPG in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.
Produktnummer ABIN1881223

Kurzübersicht für COPG Antikörper (C-Term) (ABIN1881223)

Target

Alle COPG Antikörper anzeigen
COPG (Coatomer Protein Complex, Subunit gamma (COPG))

Reaktivität

  • 15
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 15
Kaninchen

Klonalität

  • 15
Polyklonal

Konjugat

  • 10
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser COPG Antikörper ist unkonjugiert

Applikation

  • 15
  • 10
  • 4
  • 1
  • 1
Western Blotting (WB)

Klon

RB41787
  • Bindungsspezifität

    • 6
    • 3
    • 1
    • 1
    • 1
    AA 721-750, C-Term

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This COPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 721-750 amino acids from the C-terminal region of human COPG.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Haltbarkeit

    6 months
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

    Rohde, Cheong, Konrad, Paiha, Mayinger, Boehmelt: "The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52689-99, (2003) (PubMed).

  • Target

    COPG (Coatomer Protein Complex, Subunit gamma (COPG))

    Andere Bezeichnung

    COPG

    Hintergrund

    The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).

    Molekulargewicht

    97718

    NCBI Accession

    NP_057212

    UniProt

    Q9Y678
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