CMIP Antikörper (C-Term)

Produktnummer ABIN1881214

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CMIP in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für CMIP Antikörper (C-Term) (ABIN1881214)

Target: CMIP (C-Maf Inducing Protein (CMIP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CMIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB42683

Produktdetails anti-CMIP Antikörper

Bindungsspezifität: AA 735-764, C-Term

Homologie: M, X

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CMIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 735-764 amino acids from the C-terminal region of human CMIP.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-CMIP Antikörper (ABIN1881214)

Audard, Zhang, Copie-Bergman, Rucker-Martin, Ory, Candelier, Baia, Lang, Pawlak, Sahali: "Occurrence of minimal change nephrotic syndrome in classical Hodgkin lymphoma is closely related to the induction of c-mip in Hodgkin-Reed Sternberg cells and podocytes." in: Blood, Vol. 115, Issue 18, pp. 3756-62, (2010) (PubMed).

Kamal, Pawlak, BenMohamed, Valanciuté, Dahan, Candelier, Lang, Guellaën, Sahali: "C-mip interacts with the p85 subunit of PI3 kinase and exerts a dual effect on ERK signaling via the recruitment of Dip1 and DAP kinase." in: FEBS letters, Vol. 584, Issue 3, pp. 500-6, (2010) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Details zu CMIP

Target: CMIP (C-Maf Inducing Protein (CMIP))

Andere Bezeichnung: CMIP

Hintergrund: CMIP plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor.

Molekulargewicht: 86331

NCBI Accession: NP_085132, NP_938204

UniProt: Q8IY22