CDCA7L Antikörper (C-Term)

Produktnummer ABIN1881189

Dieses Anti-CDCA7L-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CDCA7L in WB. Geeignet für Human. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für CDCA7L Antikörper (C-Term) (ABIN1881189)

Target: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDCA7L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB43388

Produktdetails anti-CDCA7L Antikörper

Bindungsspezifität: AA 290-317, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CDCA7L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-317 amino acids from the C-terminal region of human CDCA7L.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-CDCA7L Antikörper (ABIN1881189)

Huang, Ho, Ponzielli, Barsyte-Lovejoy, Bouffet, Picard, Hawkins, Penn: "Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells." in: Cancer research, Vol. 65, Issue 13, pp. 5607-19, (2005) (PubMed).

Chen, Ou, Chen, Choi, Shih: "R1, a novel repressor of the human monoamine oxidase A." in: The Journal of biological chemistry, Vol. 280, Issue 12, pp. 11552-9, (2005) (PubMed).

Scherer, Cheung, MacDonald, Osborne, Nakabayashi, Herbrick, Carson, Parker-Katiraee, Skaug, Khaja, Zhang, Hudek, Li, Haddad, Duggan, Fernandez, Kanematsu, Gentles, Christopoulos, Choufani, Kwasnicka et al.: "Human chromosome 7: DNA sequence and biology. ..." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, (2003) (PubMed).

Details zu CDCA7L

Target: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Andere Bezeichnung: CDCA7L

Hintergrund: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways, May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

UniProt: B3KTR5